Valvular & structural heart diseaseResearch article
Transcatheter Aortic Valve Replacement Beyond Severe Aortic Stenosis
- Narrative review
Study context
- Population
- Patients considered for transcatheter aortic valve replacement (TAVR) beyond symptomatic severe aortic stenosis (AS) (bicuspid valve, small annuli, low-flow low-gradient AS, younger, asymptomatic severe and moderate AS, native aortic regurgitation, valve-in-valve)
Main finding
As reported in the abstract
Evidence on TAVR in populations beyond symptomatic severe AS
- Eligible population expanded to bicuspid aortic valve with feasible anatomy, small aortic annuli, low-flow low-gradient AS and younger patients
- Focus shifted to asymptomatic severe and moderate AS, as early valve replacement may prevent irreversible cardiac remodeling
- Dedicated devices for native aortic regurgitation: encouraging short-term outcomes
- Valve-in-valve TAVR: encouraging midterm results
Original publication
Transcatheter Aortic Valve Replacement Beyond Severe Aortic Stenosis. J Am Coll Cardiol. Published 11 March 2025. doi:10.1016/j.jacc.2024.11.051
Summarised from the published abstract; every number is checked against it