Valvular & structural heart diseaseCohort study
Transcatheter Edge-to-Edge Repair in Patients With Primary Tricuspid Regurgitation
- Multicentre registry cohort study
- single-group
Authors' conclusion
TEER is a safe and effective option for primary TR, promoting right heart reverse remodeling and symptomatic relief, offering a vital alternative to surgery in selected patients.
Study context
- Population
- Patients with primary tricuspid regurgitation (TR) undergoing transcatheter edge-to-edge repair (TEER), December 2016 to April 2023
- Participants
- 114 patients
- Outcome
- TR reduction to moderate or less
- Follow-up
- Discharge
Main finding
As reported in the abstract
TR reduction to moderate or less at discharge
TR reduction to moderate or less
83.3%
Observational data: associations, not effects.
Further findings
Device deployment
- Device deployment achieved
- 95.6%
TR moderate or less · 1 year
- Patients with TR moderate or less
- 79.7%
Right heart remodelling · 1 year
- Vena contracta change −5.0 mm
- P < 0.001
- Annular diameter change −2.0 mm
- P = 0.003
- Mid RV diameter change −3.0 mm
- P < 0.001
NYHA class I or II · 1 year
- NYHA I or II: 17.1% at baseline vs 66.5% at follow-up
- P < 0.001
In-hospital mortality and single-leaflet device attachment
- In-hospital mortality
- 1.8%
- Single-leaflet device attachment
- 3.5%
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Transcatheter Edge-to-Edge Repair in Patients With Primary Tricuspid Regurgitation. JACC Cardiovasc Interv. Published 26 May 2025. doi:10.1016/j.jcin.2025.03.023
Summarised from the published abstract; every number is checked against it