Valvular & structural heart diseaseCohort study
Trends and Late Outcomes in Elderly Patients Undergoing Mitral Valve Interventions in the United States
- Retrospective cohort study
- Medicare claims database
Authors' conclusion
Mitral valve interventions in elderly patients are increasing over time, driven by transcatheter therapies. Five-year mortality varied by type of intervention and was significantly influenced by frailty and social vulnerability.
Study context
- Population
- Medicare fee-for-service patients ≥65 years hospitalized for surgical or transcatheter mitral valve intervention, 2017–2022
- Participants
- 172,478 mitral valve interventions
- Exposure
- Surgery vs transcatheter mitral valve replacement (TMVR) vs M-TEER
- Outcome
- Mortality
- Follow-up
- 5 years
Main finding
As reported in the abstract
5-year mortality
Observational data: associations, not effects.
Further findings
In-hospital mortality
5-year mortality by frailty risk (subgroup)
Low frailty
Intermediate frailty
High frailty
Use trends per 100,000 Medicare Part A beneficiaries
- All mitral valve interventions increased
- 9.2%
- Surgery declined
- 15.7%
- M-TEER increased
- 94.8%
- TMVR increased
- 100%
Mortality by social vulnerability quartile
- Quartiles of social vulnerability incrementally associated with higher mortality
Original publication
Trends and Late Outcomes in Elderly Patients Undergoing Mitral Valve Interventions in the United States. JACC Cardiovasc Interv. Published 22 September 2025. doi:10.1016/j.jcin.2025.06.041
Summarised from the published abstract; every number is checked against it