Arrhythmias & electrophysiology
Trends in atrial fibrillation-related mortality in Europe, 2008–2019
Authors' conclusion
Over the last decade, the age-adjusted AF-related mortality has increased in Europe, especially among males. Disparities still exist between Western and Eastern European countries.
Study context
- Population
- European countries, atrial fibrillation (AF) (ICD-10 I48) as underlying cause of death, 2008–2019
- Participants
- 773,750 AF-related deaths
- Outcome
- Age-adjusted AF-related mortality rate (AAMR) trend, average annual % change (AAPC)
- Follow-up
- 2008–2019
Methodological detailsWHO mortality dataset, Joinpoint regression
- WHO mortality dataset
- Joinpoint regression
Main finding
As reported in the abstract
AAMR per 100 000 population
Age-adjusted mortality rate (AAMR) in 2008 (95% CI 11.2-12.9) per 100 000
12.3
AAMR in 2019 (95% CI 14.7-15.7) per 100 000
15.3
AAPC overall (95% CI 1.6-3.5), P < 0.001
+2.0%
Observational data: associations, not effects.
Further findings
AAMR trend by sex · 2008–2019
| AAPC (95% CI) | P value | |
|---|---|---|
| Men | +2.7% (1.9–3.5) | P < 0.001 |
| Women | +1.7% (1.1–2.3) | P < 0.001 |
- AAMR trend by sex — More pronounced increase among men vs women
- P for parallelism 0.01
- AAMR trend by sex: AF-related deaths: 202 552 males, 571 198 females
AAMR increase by country
- Higher AAMR increases in some Eastern European countries (Latvia, Lithuania, Poland); lower increases mainly in Central Europe
Original publication
Trends in atrial fibrillation-related mortality in Europe, 2008–2019. Eur Heart J Qual Care Clin Outcomes. Published 30 January 2024. doi:10.
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