Acute cardiac care & resuscitationCohort study

Trends in Cardiac Arrest Mortality Among Young Adults in the United States, 1999 to 2024

JACC AdvPublished

  • death certificate data analysis
  • Centers for Disease Control and Prevention Wide-Ranging Online Data for Epidemiologic Research database
  • JoinPoint regression analysis

Authors' conclusion

CA-related mortality in those aged 15 to 44 years exhibited fluctuating trends, with a notable rise between 2018 and 2021, followed by a decline through 2024. Males, NH Black Americans, and rural areas had higher mortality rates.

Study context

Population
Individuals aged 15 to 44 years in the United States, 1999 to 2024deaths attributed to cardiac arrest (CA)
Participants
289,237 individuals
Exposure
Mortality trends associated with CA in young adults, focusing on demographic and regional disparities

Main finding

As reported in the abstract

AAMR trend · 1999 to 2024

annual percentage change, 2018 to 2021

16.50% (95% CI: 8.88%-19.87%)

Observational data: associations, not effects.

Further findings

OutcomeValues
AAMR by sexMales AAMR 11.06 · Females AAMR 7.33
Average AAMR by race and ethnicityNH Black or African American average AAMR 18.68 · Hispanic/Latino average AAMR 7.92 · NH White average AAMR 7.81 · NH other average AAMR 6.00
AAMR by urbanizationRural areas AAMR 12.04 · Urban areas AAMR 8.30

AAMR by region · 2024

Western region highest AAMR
10.47

Original publication

Trends in Cardiac Arrest Mortality Among Young Adults in the United States, 1999 to 2024. JACC Adv. Published 3 July 2026. doi:10.1016/j.jacadv.2026.102973

Summarised from the published abstract; every number is checked against it