Prevention & lipidsCross-sectional study

Trends in cardiovascular risk factors control among US adults by glycemic statuses, 2007–2018

Eur J Prev CardiolPublished

  • Serial cross-sectional study
  • nationally representative
  • NHANES 2007-2008 to 2017-2018

Authors' conclusion

In this nationally representative cross-sectional study, we systematically estimated the cardiovascular risk factors control in American adults and found poor weight control in the normoglycemia and prediabetes group. Despite the significant decrease trend of plasma total cholesterol in all groups, the high cholesterol level in the prediabetes group deserves special concern.

Study context

Population
Non-pregnant US adults aged ≥20 years, NHANES 2007–2008 to 2017–2018
Participants
33,040 adults
Exposure
CV risk factor control by glycemic status over time
Outcome
Trends in CV risk factors (weight, BP, plasma cholesterol, smoking) by glycemic status
Follow-up
2007-2008 to 2017-2018

Main finding

As reported in the abstract

CV risk factor control trends, 2007-2008 to 2017-2018

Mean difference

−5.34%

95% CI −15.28% to 4.59%

P = 0.298 for trend

Diabetes
mean difference −5.34% (95% CI −15.28% to 4.59%); P for trend = 0.298
Age-adjusted mean total cholesterol decreased in all three groups; lowest in diabetes
P for trend < 0.010

Observational data: associations, not effects.

Further findings

Sensitivity analysis (second definition of prediabetes and diabetes)

Consistent trend

Original publication

Trends in cardiovascular risk factors control among US adults by glycemic statuses, 2007–2018. Eur J Prev Cardiol. Published 17 March 2023. doi:10.1093/eurjpc/zwad080

Summarised from the published abstract; every number is checked against it