Prevention & lipidsCross-sectional study

Trends in the Co-Occurrence of Alcohol Use and Cardiovascular Disease Among U.S. Adults, 1999 to 2023

JACC AdvPublished

  • Joinpoint regression analysis of 11 cycles of the National Health and Nutrition Examination Survey
  • stratified by age, sex, race/ethnicity, poverty-income ratio and educational attainment

Authors' conclusion

From 1999 to 2023, the co-occurrence of heavy alcohol use and CVD increased substantially, especially among certain demographic groups.

Study context

Population
U.S. adults, National Health and Nutrition Examination Survey 1999–202311 cycles of NHANES, 5,180 had cardiovascular disease (CVD)
Participants
43,465 adults
Exposure
Trends in co-occurrence of alcohol use and overall and type-specific CVD

Main finding

As reported in the abstract

Prevalence of heavy drinking among those with CVD · 1999 to 2000 to 2021 to 2023

1999 to 2000

17.1%

2021 to 2023

33.4%

Observational data: associations, not effects.

Further findings

Prevalence of co-occurrence of heavy drinking and CVD in overall population

Increased from
1.4%
to
3.0%
Annual percentage change (APC)
3.4%; 95% CI: 2.0%-5.1%

Co-occurrence of heavy drinking with type-specific CVD

heart failure APC
3.8%
angina APC
1.7%
stroke APC
5.2%

Co-occurrence of nondrinking and low-to-moderate drinking with CVD

nondrinking with CVD declined
−1.4%
low-to-moderate drinking with CVD remained stable

Subgroup trends in co-occurrence of heavy drinking and CVD

Increases appeared more pronounced in adults aged 40 to 59 years (post-2007), women, non-Hispanic Whites, and those with lower poverty-income ratio or educational attainment

Original publication

Trends in the Co-Occurrence of Alcohol Use and Cardiovascular Disease Among U.S. Adults, 1999 to 2023. JACC Adv. Published 21 May 2026. doi:10.1016/j.jacadv.2026.102819

Summarised from the published abstract; every number is checked against it