Prevention & lipidsCross-sectional study
Triglyceride-Glucose-Waist-to-Height Ratio Index and Left Ventricular Diastolic Function in Military Athletes
- cross-sectional analysis
Authors' conclusion
TyG-WHtR is age-independently associated with subclinical LVDF decline and lower exercise capacity in young, physically active military personnel. Whether insulin resistance reduction could improve diastolic function requires further study.
Study context
- Population
- Male and female military personnel aged 18 to 44 years151 male and 25 female military personnel · male 151 · female 25
- Exposure
- Higher-TyG-WHtR men vs Lower-TyG-WHtR men
Main finding
As reported in the abstract
TyG-WHtR and characteristics, higher- vs lower-TyG-WHtR men
| Group | Value | age |
|---|---|---|
| Higher-TyG-WHtR men | Triglyceride-glucose-waist-to-height ratio (TyG-WHtR) 4.41 (interval as printed [4.13, 4.74]) | 29 [23, 36] years |
| Lower-TyG-WHtR men | TyG-WHtR 3.62 (interval as printed [3.38, 3.82]) | 25 [21, 30] years |
Observational data: associations, not effects.
Further findings
Age-independent correlation of TyG-WHtR with e' velocity and E/A
- e' velocity τ
- −0.382; 95% CI: −0.462 to −0.297
- E/A τ
- −0.265; −0.367 to −0.165
- Benjamini-Hochberg-adjusted P < 0.001
e' velocity, multivariable regression
- TyG-WHtR leading e' predictor, standardized β
- −0.367; −0.491 to −0.242
Sex × TyG-WHtR interaction on e' velocity
- statistically detectable
- P = 0.012
- underpowered
Original publication
Triglyceride-Glucose-Waist-to-Height Ratio Index and Left Ventricular Diastolic Function in Military Athletes. JACC Adv. Published 18 June 2026. doi:10.1016/j.jacadv.2026.102865
Summarised from the published abstract; every number is checked against it