Coronary disease & ACSCohort study
Type D personality as a risk factor for 3-year cardiovascular events in patients with coronary artery disease and their spouse: a prospective cohort study
- Prospective cohort study
Authors' conclusion
This study suggests that having Type D personality, either in the CAD patient or their spouse, is associated with an increased risk of adverse cardiovascular outcomes in both individuals.
Study context
- Population
- Coronary artery disease (CAD) patients undergoing first coronary intervention and their spouses, recruited January 2017 to July 2020CAD patients and their spouses
- Participants
- 4,035 patients
- Exposure
- Type D personality in CAD patients and their spouses
- Outcome
- MACE in patients and spouses
- Follow-up
- 3 years
Main finding
As reported in the abstract
3-year MACE
Type D(+) patient/Type D(+) spouseHazard ratio (95% CI)P value
patients; highest risk
3.834(2.947–4.987)
P < 0.001spouses; highest risk
2.670(1.603–4.448)
P < 0.001- Patients developing major adverse cardiac event (MACE)
- 871
- Spouses developing MACE
- 234
Observational data: associations, not effects.
Further findings
MACE by patient × spouse negative affectivity interaction (Type D as continuous)
| Comparison | HR (95% CI) | P value | |
|---|---|---|---|
| NA_patient × NA_spouse · CAD patients · synergistic interaction | 1.746 (1.517–2.010) | P < 0.001 | |
| NA_patient × NA_spouse · spouses · synergistic interaction | 1.992 (1.843–2.152) | P < 0.001 | |
| 0.512Hazard ratio (log scale) |
Original publication
Type D personality as a risk factor for 3-year cardiovascular events in patients with coronary artery disease and their spouse: a prospective cohort study. Eur J Prev Cardiol. Published 27 November 2024. doi:10.1093/eurjpc/zwae377
Summarised from the published abstract; every number is checked against it