Heart failure & cardiomyopathies
U-Shaped Association Between Serum Calcium and In-Hospital Mortality in Patients with Congestive Heart Failure
Authors' conclusion
Our study identifies a U-shaped association between serum calcium levels and in-hospital mortality in CHF patients, with a notable inflection point at 8.35 mg/dL.
Study context
- Population
- Congestive heart failure (CHF) patients, Medical Information Mart for Intensive Care database
- Participants
- 15,983 patients
- Exposure
- Serum calcium quintiles
- Outcome
- In-hospital mortality
Main finding
As reported in the abstract
Each group vs Q3Odds ratio (95% CI)P value
Q1
1.38(1.13–1.68)
P = 0.002Q5
1.23(1.01–1.5)
P = 0.038- Effect size below threshold
- 0.782 (95% CI: 0.667-0.915, P = 0.0023)
- Effect size above threshold
- 1.147 (95% CI: 1.034-1.273, P = 0.0094)
Observational data: associations, not effects.
Further findings
- Stratified analyses confirmed the robustness of this correlation
Original publication
U-Shaped Association Between Serum Calcium and In-Hospital Mortality in Patients with Congestive Heart Failure. ESC Heart Fail. Published 11 March 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →