Heart failure & cardiomyopathiesCohort study
U-shaped Catheter Strategy for Percutaneous Endocardial Septal Radiofrequency Ablation in Hypertrophic Obstructive Cardiomyopathy: A Retrospective Comparative Study
- single-center retrospective study
- matched controls
- guided by three-dimensional electroanatomical mapping and intracardiac echocardiography
Authors' conclusion
The U-shaped catheter strategy for PESA was associated with improved procedural efficiency and greater reduction in LVOT obstruction compared with the conventional catheter approach, while maintaining a favorable safety profile.
Study context
- Population
- Patients with hypertrophic obstructive cardiomyopathy (HOCM) undergoing PESApatients with HOCM undergoing PESA · U group 15 · C group 12
- Participants
- 27 patients
- Exposure
- novel U-shaped catheter strategy with the conventional retrograde catheter approach during PESA
- U groupn = 15
- C groupn = 12
Main finding
As reported in the abstract
- Both groups demonstrated significant improvements
Observational data: associations, not effects.
Further findings
Catheter-tissue contact force · significantly higher in the U group
P < 0.01
Total radiofrequency delivery time · shorter in the U group
P = 0.01
Resting LVOT gradient · 12 months · significantly lower in the U group
P = 0.03
Safety
Major complications; transient atrioventricular (AV) block and left bundle branch block (LBBB)
- No major complications occurred in either group
- Transient AV block and LBBB were observed but required no further intervention
Original publication
Summarised from the published abstract; every number is checked against it