Coronary disease & ACSCohort study
Ultra-Low-Dose Noise-Free Technology to Reduce Radiation Exposure During Coronary Angiography
- comparative study on a single-center, real-world, observational cohort
Authors' conclusion
The Noise-Free technique reduced radiation exposure across cumulative and rate metrics while preserving diagnostic image quality, with the greatest reduction observed in complex cases. These findings support its clinical utility for lowering radiation risk.
Study context
- Population
- Patients undergoing coronary angiography or percutaneous coronary intervention (PCI) (diagnostic coronary angiography, single-vessel PCI, or chronic total occlusion PCI) using 4 different angiography systemsprocedures in 380 patients · coronary angiography 102 · single-vessel PCI 78 · chronic total occlusion PCI 200
- Participants
- 380 patients
- Exposure
- ultra-low-dose technique vs the other 3 angiography systems
- Outcome
- Procedural radiation exposure (dose area product, air kerma, dose rate), stratified by exposure mode and procedure type
Main finding
As reported in the abstract
| Group | Coronary angiography total air kerma | Coronary angiography total dose area product | Coronary angiography fluoroscopy dose rate | Coronary angiography cine dose rate |
|---|---|---|---|---|
| ultra-low-dose Noise-Free technology | 60.3 (38.5-74.1) mGy | 4.0 (2.9-5.2) Gy·cm 2 | 7.9 (6.0-9.6) mGy/min | 51.7 (37.4-64.9) mGy/min |
- Coronary angiography reductions than others: total air kerma
- 40% to 70%
- Coronary angiography reductions than others: total dose area product
- 37% to 66%
- Coronary angiography reductions than others: fluoroscopy dose rate
- 16% to 62%
- Coronary angiography reductions than others: cine dose rate
- 25% to 79%
- Chronic total occlusion PCI reduction relative to the other 3 systems: total air kerma
- 59% to 73%
- Chronic total occlusion PCI reduction relative to the other 3 systems: total dose area product
- 54% to 69%
- Chronic total occlusion PCI reduction relative to the other 3 systems: fluoroscopy dose rate
- 22% to 64%
- Chronic total occlusion PCI reduction relative to the other 3 systems: cine dose rate
- 60% to 79%
Observational data: associations, not effects.
Secondary outcomes
Baseline patient characteristics, procedural time, operator experience
- No significant difference
Image quality (expert semi-quantitative assessment and contrast-to-noise ratio)
- Comparable image quality between the 4 systems
- secondary end point
Original publication
Ultra-Low-Dose Noise-Free Technology to Reduce Radiation Exposure During Coronary Angiography. Circ Cardiovasc Interv. Published 21 April 2026. doi:10.1161/circinterventions.126.016542
Summarised from the published abstract; every number is checked against it