Unfavorable Social Determinants of Health and Obesity: A Double Jeopardy for Premature Mortality
Main finding · Premature mortalityResult — go to the resultHazard ratio 3.53 95% CI 2.81–4.45Study context
- Population
- US adults aged 18 to 64, 2013–2018 National Health Interview Survey; 38-item social determinants of health (SDoH) index
- Participants
- 136,816 adults
- Exposure
- High SDoH burden and class 3 obesity vs favourable SDoH and no obesity
- Outcome
- Premature mortality (all-cause death before age 65)
Methodological detailsNational Health Interview Survey linked to National Death Index, multivariable Cox regression
- National Health Interview Survey linked to National Death Index
- Multivariable Cox regression
Main finding
Premature mortality
Hazard ratio
3.53
95% CI 2.81–4.45
High SDoH (Q3/Q4) + class 3 obesityvs Favourable SDoH + no obesity
HR 3.53 (95% CI 2.81–4.45)
As reported in the abstract
Observational data: associations, not effects.
Further findings
Characteristics of participants with obesity
- More likely non-Hispanic Black, low income, lower education, food insecurity, no health insurance
Original publication
Unfavorable Social Determinants of Health and Obesity: A Double Jeopardy for Premature Mortality. JACC Adv. Published 8 October 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →