Arrhythmias & electrophysiology

Unipolar voltage electroanatomic mapping detects structural atrial remodeling identified by late gadolinium enhancement magnetic resonance imaging (LGE-MRI)

Heart RhythmPublished Diagnostic accuracy study

Authors' conclusion

Our findings demonstrate that unipolar LVAs strongly correlate with LGE regions.

Study context

Population
Patients scheduled for atrial fibrillation (AF) ablation undergoing preablation LGE-MRI and high-density electroanatomic mapping (EAM) in sinus rhythm
Participants
20 patients
Comparison
Unipolar vs bipolar low-voltage areas for identifying LGE regions
Outcome
Correspondence between LGE areas and LVAs in the left atrial (LA) (confusion matrices, performance metrics)
Methodological detailsmultipolar high-density mapping, coregistration of EAM and LGE-MRI
  • Multipolar high-density mapping
  • Coregistration of EAM and LGE-MRI

Performance

As reported in the abstract

Identification of LGE areas
StrategySensitivityPrecisionF1 scoreAccuracy
Unipolar low-voltage areas (LVAs)87.3%78.6%81.3%74.0%
Bipolar LVAs16.2%61.1%26.0%35.3%

Sensitivity

Unipolar low-voltage areas (LVAs)87.3%
Bipolar LVAs16.2%

Precision

Unipolar low-voltage areas (LVAs)78.6%
Bipolar LVAs61.1%

F1 score

Unipolar low-voltage areas (LVAs)81.3%
Bipolar LVAs26.0%

Accuracy

Unipolar low-voltage areas (LVAs)74.0%
Bipolar LVAs35.3%
LGE regions overlapping unipolar LVAs
87.3%
LGE regions overlapping bipolar LVAs
16.2%

Original publication

Unipolar voltage electroanatomic mapping detects structural atrial remodeling identified by LGE-MRI. Heart Rhythm. Published 11 October 2024. doi:10.1016/j.hrthm.2024.10.015

Summarised from the published abstract; every number is checked against it

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