Congenital heart diseaseCross-sectional study
Use of new paediatric VO2max reference equations to evaluate aerobic fitness in overweight or obese children with congenital heart disease
- Cross-sectional study
- controlled
- matched comparisons
Authors' conclusion
As opposed to the existing linear models, the new paediatric VO2max Z-score equations can discriminate the aerobic fitness of obese/overweight children with CHD from that of obese/overweight children without any chronic disease.
Study context
- Population
- Children with body mass index (BMI) > 85th percentile undergoing cardiopulmonary exercise test (CPET)54% boys
- Participants
- 344 children
- Exposure
- CHD vs Controls
- CHDn = 100
- Controlsn = 244reference
- Outcome
- Aerobic fitness by paediatric VO2max Z-score reference equations
Main finding
As reported in the abstract
VO2max Z-score
CHD
−0.43
mean · SD 1.27
Controls
−0.01
mean · SD 1.09
P = 0.02
Observational data: associations, not effects.
Further findings
Impaired aerobic fitness (Z-score equations) · matched controls
P = 0.02
Complex CHD at risk of impaired aerobic fitness
- Z-score equations identified univentricular heart and right outflow tract anomalies as at risk
Aerobic fitness by Cooper's weight- and height-based linear equations
- No significant group differences
Original publication
Use of new paediatric VO2max reference equations to evaluate aerobic fitness in overweight or obese children with congenital heart disease. Eur J Prev Cardiol. Published 14 June 2023. doi:10.1093/eurjpc/zwad201
Summarised from the published abstract; every number is checked against it