Heart failure & cardiomyopathies
Usefulness of Oxygen Uptake Efficiency Slope in a 6 Min Walk Test in Chronic Heart Failure
Authors' conclusion
In frail patients with CHF who have difficulty performing maximal exercises, the OUES through the 6MWT may be applied instead of the OUES and peak VO2 from the CPET.
Study context
- Population
- Patients with chronic heart failure (HF) who underwent both 6MWT with portable gas analysis and cardiopulmonary exercise test (CPET), December 2016–May 202050% male
- Participants
- 40 patients
- Exposure
- 6MWT vs CPET
- Outcome
- Correlation of 6MWT parameters with OUES in CPET
Main finding
As reported in the abstract
Oxygen uptake efficiency slope (OUES) in 6MWT vs OUES in CPET, r
r = 0.729, P < 0.001
6MWD vs OUES in CPET, r
r = 0.434, P = 0.005
Observational data: associations, not effects.
Further findings
Peak VO2
| Outcome | 6MWT | CPET |
|---|---|---|
| OUES | 1528.87 (SD 579.01) | 1638.69 (SD 601.31) |
- Peak VO2: 6MWT peak VO2 only 74% of CPET peak VO2
Correlation of OUES 6MWT vs CPET, by CPET peak VO2 (subgroup)
- Peak VO2 ≥ 20 mL/kg/min
- r = 0.661, P = 0.001
- Peak VO2 < 20 mL/kg/min
- r = 0.526, P = 0.021
Correlation of 6MWT parameters with peak VO2 in CPET
- 6MWD
- r = 0.627, P < 0.001
- OUES
- r = 0.452, P = 0.003
- Peak VO2
- r = 0.492, P = 0.001
Original publication
Usefulness of Oxygen Uptake Efficiency Slope in a 6 Min Walk Test in Chronic Heart Failure. ESC Heart Fail. Published 26 March 2024. doi:10.
Summarised from the published abstract; every number is checked against it