Arrhythmias & electrophysiologyResearch article

Using Atrial Cardiomyopathy Metrics to Characterize Atrial Fibrillation in Endurance Athletes

JACC Clin ElectrophysiolPublished

  • Development of an atrial fibrillation (AF) probability model (logistic regression) in endurance athletes and nonathletic control subjects

Authors' conclusion

A combination of atrial cardiomyopathy markers was associated with high AF prevalence in EAs. A resulting quantitative AF risk identification tool provides promise for interventions aimed at preventing AF and thromboembolic complications in EAs.

Study context

Population
Endurance athletes and nonathletic control subjectsEndurance athletes (EAs) 353 · NAs 97
Participants
353 vs 97
Comparison
EAs with prevalent AF vs EAs without AF
  • EAsn = 353
  • NAsn = 97

Main finding

As reported in the abstract

LA volume, EAs vs NAs

40% larger; P < 0.001

Further findings

Atrial cardiomyopathy markers, EAs with AF vs EAs without AF

LA volume EAs with AF 46.2 mL/m² · EAs without AF 41.9 mL/m²

LA strain (reservoir)

P-wave duration EAs with AF 124 ms · EAs without AF 111 ms

Abnormal P-wave terminal force velocity in lead V1

PACs EAs with AF 118 PACs/24 h · EAs without AF 15 PACs/24 h

  • Atrial cardiomyopathy markers, EAs with AF vs EAs without AF: all P < 0.001

Prevalent AF among EAs

EAs with prevalent AF
96 (27%)

Clinical risk model discrimination

AUC
0.84

High AF-PRS and AF odds

High AF-PRS increased AF odds
2.56-fold
Contributed little additional predictive value

AF prevalence by model risk category

Low risk athletes
4%
Very high risk athletes
86%

Original publication

Using Atrial Cardiomyopathy Metrics to Characterize Atrial Fibrillation in Endurance Athletes. JACC Clin Electrophysiol. Published 23 April 2026. doi:10.1016/j.jacep.2026.03.010

Summarised from the published abstract; every number is checked against it