Coronary disease & ACSSecondary analysis

Validity of the International Classification of Diseases, Tenth Revision codes in diagnosing myocardial infarction subtypes

Am Heart JPublished

  • secondary analysis of a single-center prospective cohort study
  • consecutive individuals

Authors' conclusion

These data suggest the ICD-10 codes for each individual MI subtype have such low sensitivity that they may not reliably and accurately identify these MI subtypes in clinical research or in quality metrics and value-based programs.

Study context

Population
Consecutive individuals who underwent highsensitivity cardiac troponin testing between October 2023 and February 2025individuals undergoing troponin testing
Participants
24,524 individuals
Comparison
Clinician adjudicated diagnoses were compared to ICD-10 codes attributable to type 1 myocardial infarction (MI), type 2 MI, and type 3-5 MI

Primary result

As reported in the abstract

Diagnostic accuracy of ICD-10 codes for MI subtypes vs clinician adjudication
Groupsensitivityspecificity
type 1 MI ICD-10 codes53%99%
type 2 MI ICD-10 codes3%99%
types 3-5 MI ICD-10 codes0%99%

Original publication

Validity of the International Classification of Diseases, Tenth Revision codes in diagnosing myocardial infarction subtypes. Am Heart J. Published 19 April 2026. doi:10.1016/j.ahj.2026.107447

Summarised from the published abstract; every number is checked against it