Coronary disease & ACSCross-sectional study
Variation in secondary prevention of coronary heart disease: the INTERASPIRE study
- Cross-sectional study
- international
- 14 countries, all 6 WHO regions
- direct age and sex standardization
Authors' conclusion
INTERASPIRE demonstrates inadequate and heterogeneous international implementation of guideline standards for secondary prevention in the first year after CHD hospitalization, with geographic and sex disparity.
Study context
- Population
- Adults hospitalized 6–24 months earlier with incident or recurrent coronary heart disease (CHD), 14 countries, 2020–202321.1% female
- Participants
- 4,548 adults
- Outcome
- Achievement of guideline standards for secondary prevention and cardiac rehabilitation
Main finding
As reported in the abstract
Guideline standards for secondary prevention · median 1.05 (IQR .76-1.45) years after index hospitalization
- Obese
- 24.6%
- Centrally obese
- 40.7%
- Blood pressure (BP) <130/80 mmHg achieved
- 38.6%
- LDL-C <1.4 mmol/L achieved
- 16.6%
- Persistent smoking among smokers at hospitalization
- 48%
- HbA1c <7.0% achieved in known DM
- 55.2%
- Undetected DM
- 9.8%
- Impaired glucose tolerance
- 26.9%
- Attended cardiac rehabilitation (inter-country range 3.8%-20.0%)
- 9.0%
- Optimal guideline adherence (inter-country range .0%-2.4%)
- 1.0%
Observational data: associations, not effects.
Further findings
Target achievement by sex
- BP target: females vs males
- 36.8% vs 38.9%
- LDL-C target: females vs males
- 12.0% vs 17.9%
- HbA1c target in DM: females vs males
- 47.7% vs 57.5%
Original publication
Variation in secondary prevention of coronary heart disease: the INTERASPIRE study. Eur Heart J. Published 30 August 2024. doi:10.1093/eurheartj/ehae558
Summarised from the published abstract; every number is checked against it