HypertensionCross-sectional study

Variations in blood pressure after a 75 g oral glucose load and their implications for detecting hypertension and postprandial hypotension in Chinese adults: a cross-sectional study

Eur J Prev CardiolPublished

  • Cross-sectional study
  • stratified multi-stage random sampling
  • nationally representative

Authors' conclusion

Ingestion of a 75 g glucose drink often lowers BP, frequently leading to PPH and influencing the detection of hypertension.

Study context

Population
Community-dwelling adults in China, April 2020–January 2021
Participants
4,429 adults
Outcome
BP responses to a 75 g glucose drink and implications for detecting hypertension and PPH
Follow-up
1 and 2 h

Main finding

As reported in the abstract

High blood pressure (BP) (≥140/90 mmHg) when fasting
38.4%
SBP decrease at 1 h, mmHg
6.2 (95% CI 5.8, 6.6)
SBP decrease at 2 h, mmHg
8.1 (95% CI 7.7, 8.5)
DBP decrease at 1 h, mmHg
4.7 (95% CI 4.4, 4.9)
DBP decrease at 2 h, mmHg
6.1 (95% CI 5.8, 6.4)
HR increase at 1 h, bpm
4.3 (95% CI 4.0, 4.5)
HR increase at 2 h, bpm
2.6 (95% CI 2.4, 2.9)
High BP at 1 h
30.9%
High BP at 2 h
27.0%
Estimated PPH prevalence (age- and sex-adjusted)
19.9%

Observational data: associations, not effects.

Further findings

PPH and combined CVD and stroke

PPH associated with increased risk of combined CVD and stroke

Original publication

Variations in blood pressure after a 75 g oral glucose load and their implications for detecting hypertension and postprandial hypotension in Chinese adults: a cross-sectional study. Eur J Prev Cardiol. Published 8 April 2025. doi:10.1093/eurjpc/zwaf217

Summarised from the published abstract; every number is checked against it