Acute cardiac care & resuscitationCohort study
Ventilation Strategies in Cardiogenic Shock: Insights from the AltShock-2 Registry
- Prospective registry study
Authors' conclusion
Compared to previous studies, we observed a rising trend in the utilization of NIV among cardiogenic shock patients, irrespective of aetiology and SCAI stages.
Study context
- Population
- Patients with cardiogenic shock, enrolled March 2020 to November 2023
- Participants
- 657 patients
- Exposure
- Non-invasive ventilation (NIV) vs invasive mechanical ventilation (iMV) vs oxygen therapy
- Oxygen therapy (OT)n = 198
- NIVn = 96
- iMVn = 363reference
Main finding
All-cause mortality · 60 days
Hazard ratio
1.97
95% CI 0.85–4.56
By group
NIV vs iMV
HR 1.97 (95% CI 0.85–4.56)
As reported in the abstract
- 60-day mortality differed across the three groups, even after excluding cardiac arrest at presentation
- P = 0.005
Observational data: associations, not effects.
Further findings
All-cause mortality · 24 h
- Did not differ amongst the three groups
Original publication
Ventilation Strategies in Cardiogenic Shock: Insights from the AltShock-2 Registry. Eur J Heart Fail. Published 6 August 2024. doi:10.1002/ejhf.3409
Summarised from the published abstract; every number is checked against it