Arrhythmias & electrophysiology

Ventricular tachycardia substrate mapping with cardiac computed tomography and cardiac magnetic resonance imaging: Head-to-head comparison of two clinically available postprocessing platforms

Heart RhythmPublished Head-to-head comparison of two clinically available postprocessing platforms

Authors' conclusion

ADAS 3D and inHEART demonstrated high concordance in scar quantification and substrate characterization, with comparable performance across cardiomyopathy types. Given their complementary strengths, platform choice should be guided by procedural goals, imaging availability, operator experience, and institutional context, as each system offers distinct advantages. Prospective studies are needed to evaluate the impact on procedural success and long-term outcomes.

Study context

Population
Patients with ischemic and nonischemic cardiomyopathy undergoing ventricular tachycardia ablation who underwent both CCT and late gadolinium enhancement cardiac magnetic resonance (CMR) before ablationpatients analyzed, 12 had detailed EAM data · ischemic 8 · nonischemic 8
Participants
16 patients
Exposure
CMR- and CCT-derived ventricular substrate models generated by ADAS 3D and inHEART
Outcome
Scar core and border zone measurements
Methodological detailsretrospective
  • Retrospective

Main finding

As reported in the abstract

Comparable between platforms in both subgroups
all P > .05

Observational data: associations, not effects.

Further findings

Visualization scores

ADAS 3D slightly higher, particularly in nonischemic cardiomyopathy; differences not statistically significant

Spatial concordance between imaging-derived scar and EAM-defined ablation areas

Good to excellent
10 of 12 cases

Original publication

Ventricular tachycardia substrate mapping with cardiac computed tomography and cardiac magnetic resonance imaging: Head-to-head comparison of two clinically available postprocessing platforms. Heart Rhythm. Published 19 September 2025. doi:10.1016/j.hrthm.2025.09.028

Composed by AI from the published abstract and checked against it. How Briefs are made →

Get them every week

New studies on this topic in My Week and in your Monday e-mail.

We e-mail you a sign-in link and a code. No password, no spam.