Arrhythmias & electrophysiology

Very-early symptomatic recurrence is associated with late recurrence after radiofrequency ablation of atrial fibrillation

EuropacePublished Prospective cohort study

Authors' conclusion

Very-early symptomatic recurrence is associated with an increased risk of LR.

Study context

Population
Atrial fibrillation (AF) patients undergoing first radiofrequency catheter ablation, Beijing Anzhen Hospital, June 2018–December 2021330 (4.79%) with VESR
Participants
6,887 patients
Exposure
VESR and/or ER vs neither, after first radiofrequency catheter ablation (RFCA) of AF
Outcome
Late recurrence (after 3 months of RFCA)
Follow-up
Average 14.7 months after grouping
Methodological detailssingle-centre
  • Single-centre

Main finding

As reported in the abstract

Late recurrence

Fold increase in LR risk (multivariate)

2.161

Group B

Fold increase in LR risk (multivariate)

5.409

Group C

Fold increase in LR risk (multivariate)

7.401

Group D

Observational data: associations, not effects.

Further findings

OutcomeFold LR riskP value
Late recurrence, by AF type (subgroup)VESR vs other patients · paroxysmal AFP < 0.001
Late recurrence, by AF type (subgroup)VESR vs other patients · persistent AFP < 0.001
Late recurrence, by VESR modeVESR-atrial tachycardia vs Group A3.467
Late recurrence, by VESR modeVESR-AF vs Group A5.564
  • Late recurrence, by AF type (subgroup): P for interaction = 0.118

Prediction of LR in VESR patients

Classification based on ER and VESR modes improved prediction of LR risk

Original publication

Very-early symptomatic recurrence is associated with late recurrence after radiofrequency ablation of atrial fibrillation. Europace. Published 7 July 2023. doi:10.1093/europace/euad189

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