Arrhythmias & electrophysiologyCohort study
Very-early symptomatic recurrence is associated with late recurrence after radiofrequency ablation of atrial fibrillation
- Prospective cohort study
- single-centre
Authors' conclusion
Very-early symptomatic recurrence is associated with an increased risk of LR.
Study context
- Population
- Atrial fibrillation (AF) patients undergoing first radiofrequency catheter ablation, Beijing Anzhen Hospital, June 2018–December 2021330 (4.79%) with VESR
- Participants
- 6,887 patients
- Exposure
- VESR and/or ER vs neither, after first radiofrequency catheter ablation (RFCA) of AF
- Outcome
- Late recurrence (after 3 months of RFCA)
- Follow-up
- Average 14.7 months after grouping
Main finding
As reported in the abstract
Late recurrence
- Group B
- fold increase in LR risk (multivariate) 2.161
- Group C
- fold increase in LR risk (multivariate) 5.409
- Group D
- fold increase in LR risk (multivariate) 7.401
Observational data: associations, not effects.
Further findings
| Outcome | fold LR risk | P value |
|---|---|---|
| Late recurrence, by AF type (subgroup) — VESR vs other patients · paroxysmal AF | P < 0.001 | |
| Late recurrence, by AF type (subgroup) — VESR vs other patients · persistent AF | P < 0.001 | |
| Late recurrence, by VESR mode — VESR-atrial tachycardia vs Group A | 3.467 | |
| Late recurrence, by VESR mode — VESR-AF vs Group A | 5.564 |
- Late recurrence, by AF type (subgroup): P for interaction = 0.118
Prediction of LR in VESR patients
- Classification based on ER and VESR modes improved prediction of LR risk
Original publication
Very-early symptomatic recurrence is associated with late recurrence after radiofrequency ablation of atrial fibrillation. Europace. Published 7 July 2023. doi:10.1093/europace/euad189
Summarised from the published abstract; every number is checked against it