Cardiometabolic & kidneyCohort study
Venous Excess Ultrasound Score (VExUS) Point-of-Care Ultrasound Tool to Detect Changes in Volume Status
- prospective observational study
Authors' conclusion
Fluid removal with HD was associated with changes in the VExUS score, highlighting the utility of VExUS to capture dynamic shifts in intravascular volume in patients with end-stage renal disease.
Study context
- Population
- Inpatients with end-stage renal disease undergoing hemodialysis (HD)92 paired ultrasound exams
- Participants
- Forty-six inpatients
- Exposure
- pre-HD and post-HD VExUS scores
- Outcome
- Change in composite VExUS score (scale 0 to 4)
- Follow-up
- Before and after hemodialysis
Main finding
As reported in the abstract
Median score decrease
1.5
95% CI 1–2
P < 0.001
Observational data: associations, not effects.
Further findings
Linear relationship between volume removed and change in VExUS score
- No significant linear relationship
- univariate linear regression
Volume of fluid removed with HD
- median volume of fluid removed
- 2,000 mL (IQR: 985-2,500 mL)
Original publication
VExUS Point-of-Care Ultrasound Tool to Detect Changes in Volume Status. JACC Adv. Published 29 January 2026. doi:10.1016/j.jacadv.2025.102538
Summarised from the published abstract; every number is checked against it