Venous Excess Ultrasound Score (VExUS) Point-of-Care Ultrasound Tool to Detect Changes in Volume Status: A Prospective Observational Study
Main finding · Change in composite VExUS score (scale 0 to 4)Result — go to the resultMedian score decrease 1.5 95% CI 1–2Authors' conclusion
Fluid removal with HD was associated with changes in the VExUS score, highlighting the utility of VExUS to capture dynamic shifts in intravascular volume in patients with end-stage renal disease.
Study context
- Population
- Inpatients with end-stage renal disease undergoing hemodialysis (HD)92 paired ultrasound exams
- Participants
- 46 inpatients
- Exposure
- pre-HD and post-HD VExUS scores
- Outcome
- Change in composite VExUS score (scale 0 to 4)
- Follow-up
- Before and after hemodialysis
Main finding
As reported in the abstract
Median score decrease
1.5
95% CI 1–2
P < 0.001
Observational data: associations, not effects.
Further findings
Linear relationship between volume removed and change in VExUS score
- No significant linear relationship
- Univariate linear regression
Volume of fluid removed with HD
- Median volume of fluid removed
- 2,000 mL (IQR: 985-2,500 mL)
Original publication
VExUS Point-of-Care Ultrasound Tool to Detect Changes in Volume Status: A Prospective Observational Study. JACC Adv. Published 29 January 2026. doi:10.
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