Valvular & structural heart disease
Venous Excess Ultrasound (VExUS) Score and Hepatorenal Congestion Improvements After Transcatheter Tricuspid Intervention: Clinical and Prognostic Insights
Authors' conclusion
TTVI improved hepatic, portal, and intrarenal venous flow within 24 hours, with sustained effects at 1 year. Postprocedure VExUS score was associated with mortality and may serve as a procedural success indicator.
Study context
- Population
- Patients undergoing transcatheter tricuspid valve intervention (TTVI), 2022–2024
- Participants
- 64 patients
- Exposure
- Venous flow before vs after TTVI
- Outcome
- Changes in hepatic, portal and intrarenal venous flow (VExUS score) before vs after TTVI
- Follow-up
- 24 hours pre- and postprocedure
Methodological detailsmulticentre
- Multicentre
Main finding
As reported in the abstract
VExUS score · 24 hours
Baseline VExUS grade 3
70%
Reclassified to VExUS ≤1 within 24 hours (hepatic vein, portal pulsatility and intrarenal venous flows improved), despite no change in diuretic dose or weight
66%
Observational data: associations, not effects.
Further findings
Mortality by postprocedure VExUS grade 3 at 24 hours
| HR (95% CI) | P value | ||
|---|---|---|---|
| VExUS grade 3 | 5.55 (1.60–19.21) | P = 0.007 | |
| 0.050.21520Hazard ratio (log scale) |
Durability of venous ultrasound improvements · follow-up (1, 6, 12 months)
- Venous ultrasound improvements persisted during follow-up
Original publication
VExUS Score and Hepatorenal Congestion Improvements After Transcatheter Tricuspid Intervention: Clinical and Prognostic Insights. JACC Cardiovasc Interv. Published 10 August 2026. doi:10.
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