Arrhythmias & electrophysiologyTrial design
Women’s health initiative strong and healthy silent atrial fibrillation recording study: Rationale, study design, and baseline data
- randomized trial
- pragmatic
- embedded within the WHI Strong and Healthy (WHISH) trial
- 40 United States clinical centers
Study context
- Population
- Postmenopausal women without baseline atrial fibrillation (AF) enrolled in Medicare Fee-for-Servicerandomized, sub-study of women at high-risk for AF (CHARGE-AF score ≥5%) with serial 7-day ECG patch monitoring · ECG patch monitoring sub-study 1,257
- Participants
- 29,758 women
- Planned comparison
- Incidence of clinical AF in the participants assigned to physical activity intervention and the participants assigned to usual care groups
- Primary endpoint
- Incident clinical AF (identified in Medicare claims)
- Follow-up
- planned 7-year follow-up
No results yet. This paper sets out the design of a trial; its results are to come.
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Women’s health initiative strong and healthy silent atrial fibrillation recording study: Rationale, study design, and baseline data. Am Heart J. Published 8 May 2026. doi:10.1016/j.ahj.2026.107478
Summarised from the published abstract; every number is checked against it