Prevention & lipidsCross-sectional study

10-Year and 30-Year Risks of Cardiovascular Disease in the U.S. Population

J Am Coll CardiolPublished

  • Cross-sectional study
  • survey-weighted
  • age-standardized

Authors' conclusion

Three in 10 U.S. adults aged 30 to 79 years have existing CVD or an elevated 10-year predicted risk of CVD, including >90% of adults aged >65 years. Two-thirds of middle-aged adults are without CVD but have an elevated 30-year CVD risk. Men and Black and Hispanic adults are higher risk.

Study context

Population
US adults aged 30 to 79 years, NHANES 2011–2020representing 160.6 million US adults
Participants
14,184 adults
Outcome
Prevalence of elevated (≥7.5%) 10-year predicted risk of total CVD (PREVENT equations)
Follow-up
10 years

Main finding

As reported in the abstract

Elevated (≥7.5%) 10-year predicted risk

Total cardiovascular disease (CVD), survey-weighted prevalence

20.2%

Atherosclerotic CVD (ASCVD)

10.7%

Heart failure (HF)

12.7%

Observational data: associations, not effects.

Further findings

Existing CVD prevalence

All adults
9.6%
Aged 65 to 79 years
26.8%

Elevated 10-year total CVD risk, by age

Aged 30 to 44 years
1.0%
Aged 45 to 64 years
18.3%
Aged 65 to 79 years
66.3%

10-year risks of total CVD, ASCVD and HF, by sex, race and ethnicity

Higher in men and in Black and Hispanic adults
Mean 10-year risks modestly increased over time

Without CVD but elevated 30-year total CVD risk

Aged 30 to 59 years
66.7%
Aged 45 to 59 years
89.7%
Men and Black adults had higher 30-year risks of ASCVD and HF

Original publication

10-Year and 30-Year Risks of Cardiovascular Disease in the U.S. Population. J Am Coll Cardiol. Published 17 June 2025. doi:10.1016/j.jacc.2025.03.546

Summarised from the published abstract; every number is checked against it