Heart failure & cardiomyopathies

2-Dimensional Echocardiographic Global Longitudinal Strain With Artificial Intelligence Using Open Data From a UK-Wide Collaborative

JACC Cardiovasc ImagingPublished Diagnostic accuracy study

Authors' conclusion

Our open-source approach to calculating GLS agrees with experts' consensus as strongly as the individual expert measurements and proprietary machine solutions.

Study context

Population
Apical 4-, 2- and 3-chamber echocardiographic images; external validation on 100 echocardiograms (Unity UK Echocardiography AI Collaborative)
Participants
100 echocardiograms
Comparison
Open machine-learning global longitudinal strain (GLS) (Unity-GLS) vs individual experts and 2 proprietary packages
Outcome
Agreement of GLS with multiexpert consensus measurement
Methodological detailsexternal validation, multiexpert consensus reference
  • External validation
  • Multiexpert consensus reference

Performance

As reported in the abstract

Agreement with expert consensus GLS
Test or modelMedian absolute errorCorrelation with consensusError
Individual experts2.00 GLS units0.85
Unity-GLS0.911.3
Proprietary A0.732.5
Proprietary B0.792.2

Median absolute error

Individual experts2.00 GLS units
Unity-GLS— not stated in the abstract
Proprietary A— not stated in the abstract
Proprietary B— not stated in the abstract

Correlation with consensus

Individual experts0.85
Unity-GLS0.91
Proprietary A0.73
Proprietary B0.79

Error

Individual experts— not stated in the abstract
Unity-GLS1.3
Proprietary A2.5
Proprietary B2.2

Further findings

OutcomeIndividual expertsUnity-GLSProprietary AProprietary B
Median GLS across 11 expertsmedian −16.1 (IQR −19.3–-12.5)— not stated in the abstract— not stated in the abstract— not stated in the abstract
Rank correlation with multiexpert visual rankingmedian rank correlation 0.720.770.700.74

— not stated in the abstract

Original publication

2-Dimensional Echocardiographic Global Longitudinal Strain With Artificial Intelligence Using Open Data From a UK-Wide Collaborative. JACC Cardiovasc Imaging. Published 10 July 2024. doi:10.1016/j.jcmg.2024.04.017

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