Arrhythmias & electrophysiology
A Community-Based Trial of Commercially Available Compression Tights in Patients With Postural Orthostatic Tachycardia Syndrome
Authors' conclusion
Commercially available compression tights reduced heart rate and symptoms both acutely and after several hours of use. This additional benefit persisted whether concomitant medications were used.
Study context
- Population
- Patients with postural orthostatic tachycardia syndrome, community-based setting, with and without heart-rate-modulating medications
- Participants
- 26 patients
- Comparison
- Compression tights on (ON) vs off (OFF)
- Primary endpoint
- Standing heart rate (Holter) and symptoms (VOSS) during 10-minute active stand tests
Methodological details2 before-after protocols, randomized crossover, community-based, Protocol #1: medications held; protocol #2: medications taken as normal; 4 stand tests each (AM-OFF, AM-ON, PM-ON, PM-OFF)
- 2 before-after protocols
- Randomized crossover
- Community-based
- Protocol #1: medications held; protocol #2: medications taken as normal; 4 stand tests each (AM-OFF, AM-ON, PM-ON, PM-OFF)
Primary result
As reported in the abstract
Standing heart rate, protocol #1 (medications held) · AM
P < 0.001
- Symptoms improved, AM-ON vs AM-OFF
- P < 0.001
Further findings
Standing heart rate, protocol #2 (medications as normal) · AM · AM-ON vs AM-OFF · spread printed in brackets, kind not named
P < 0.001
- Standing heart rate, protocol #2 (medications as normal) — Symptoms improved, AM-ON vs AM-OFF
- P = 0.03
Removal of compression after several hours, protocol #1 · PM
- Standing heart rate increased
- P = 0.04
- Symptoms increased
- P = 0.004
Removal of compression after several hours, protocol #2 · PM
- Standing heart rate increased
- P = 0.02
- Symptoms increased
- P < 0.001
Original publication
A Community-Based Trial of Commercially Available Compression Tights in Patients With Postural Orthostatic Tachycardia Syndrome. JACC Clin Electrophysiol. Published 27 November 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →