Coronary disease & ACS

A Mobile Application for STEMI Care Optimization in a Multicenter Health System

JACC AdvPublished observational comparison

Authors' conclusion

In this observational multicenter implementation study, App-managed STEMI activations were associated with shorter transfer-related time metrics and higher attainment of guideline-relevant time thresholds across 2 interfacility pathways.

Study context

Population
STEMI activations in a multicenter health care system, across 2 interfacility transfer routes and 1 percutaneous coronary intervention-capable local pathway
Exposure
STEMI activations managed through the App vs the traditional workflow
Outcome
Composite:
  • Door-to-device (D2D)
  • Combined transfer pathway door-in-door-out (DIDO) times
Methodological detailsmulticenter implementation study
  • Multicenter implementation study

Main finding

As reported in the abstract

Hodges-Lehmann reduction

16 min

95% CI 8–24P < 0.001

composite door-to-device (D2D); reduction with App

Hodges-Lehmann reduction

12 min

95% CI 6–19P < 0.001

combined transfer pathway door-in-door-out (DIDO); reduction with App

Traditional workflow

Composite D2D
92 min (IQR: 63-110)
Combined transfer pathway DIDO
57.5 min (IQR: 48.3-70.8)

App

Composite D2D
71 min (IQR: 60-85)
Combined transfer pathway DIDO
46.0 min (IQR: 39.5-57.5)

Composite D2D

Traditional workflow92 min (IQR: 63-110)
App71 min (IQR: 60-85)

Combined transfer pathway DIDO

Traditional workflow57.5 min (IQR: 48.3-70.8)
App46.0 min (IQR: 39.5-57.5)

Observational data: associations, not effects.

Further findings

D2D target attainment according to pathway-specific registry benchmarks

P < 0.001

Proportion of transfer cases achieving DIDO ≤45 min

P = 0.006

D2D and DIDO by pathway

D2D and DIDO improved in both interhospital transfer pathways
Local pathway showed no significant improvement

Original publication

A Mobile Application for STEMI Care Optimization in a Multicenter Health System. JACC Adv. Published 31 October 2026. doi:10.1016/j.jacadv.2026.103413

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