Coronary disease & ACS

Effect of an integrated care model on ST-segment elevation myocardial infarction management in China: a prospective, multicentre, non-randomised controlled study

HeartPublished prospective, multicentre, non-randomised controlled study

Authors' conclusion

Use of an integrated care model focusing on prehospital delay may increase the rate of timely treatment in areas with limited medical resources in China.

Study context

Population
Patients with acute STEMI admitted to tertiary hospitals in different regions of China (August 2015-February 2019)patients with acute STEMI analysed · intervention group 2,452 · control group 4,365
Participants
6,817 patients
Comparison
Integrated care model vs usual care
  • Interventionn = 2,452
  • Controln = 4,365
Primary endpoint
Proportion of patients receiving symptom-to-reperfusion within 12 hours
Follow-up
Between 2015 and 2019
Methodological detailsconsecutively enrolled, eight tertiary hospitals in different regions of China
  • Consecutively enrolled
  • Eight tertiary hospitals in different regions of China

Primary result

As reported in the abstract

Symptom-to-reperfusion within 12 hours, intervention group, increase

from 65.3% to 91.4%

Further findings

OutcomeP value
In-hospital mortality and major adverse cardiac eventsIntervention group vs control group · nearly onefold decrease in the intervention groupP < 0.001

Symptom-to-admission within 12 hours · Between 2015 and 2019

Intervention group, increase
from 74.2% to 96.4%
  • Ptrend=0.015

Door-to-balloon time within 90 min

No significant difference among the two groups; adjusted relative risk
0.96, 95% CI: 0.89 to 1.02; p=0.18

Baseline characteristics

Age (mean±SD)
61±13 years
Female
n=1242 (18.2%)

Original publication

Effect of an integrated care model on ST-segment elevation myocardial infarction management in China: a prospective, multicentre, non-randomised controlled study. Heart. Published 9 September 2025. doi:10.1136/heartjnl-2024-324155

Summarised from the published abstract; every number is checked against it

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