Arrhythmias & electrophysiology
A novel electrocardiogram (ECG) algorithm for accurate localization of manifest accessory pathways in both children and adults: SMART-WPW
Authors' conclusion
The SMART-WPW algorithm is an accurate, efficient, and reproducible tool for 12-lead ECG-based AP localization. Its use may enhance preprocedural assessment and ablation planning in WPW syndrome.
Study context
- Population
- Patients with a single manifest accessory pathway undergoing Wolff-Parkinson-White (WPW) ablation, children and adultspatients with a single manifest accessory pathway (AP) undergoing WPW ablation, mean age 34 ± 19 years, 51% female · children younger than 18 years 76
- Participants
- 260 patients
- Index test or model
- SMART-WPW algorithm compared with established Pambrun and Arruda algorithms
- Target condition
- AP location
Methodological detailsalgorithm developed and prospectively tested
- Algorithm developed and prospectively tested
Performance
As reported in the abstract
Accuracy
97% vs 90%
P = 0.015
SMART-WPW algorithm vs Pambrun algorithm
Accuracy
97% vs 73%
P < 0.001
SMART-WPW algorithm vs Arruda algorithm
Further findings
| Outcome | SMART-WPW algorithm | Arruda algorithm | Accuracy | P value |
|---|---|---|---|---|
| Accuracy in children younger than 18 years (subgroup, n = 76; mean age 14 ± 3 years; 61% female)SMART-WPW algorithm vs Arruda algorithm | 97% | 62% | 97% vs 62% | P < 0.001 |
Accuracy by AP location
- Right-sided APs between 4 and 8 o'clock
- 100% sensitivity and specificity
- Left-sided APs between 5 and 8 o'clock
- 100% sensitivity and specificity
Original publication
A novel ECG algorithm for accurate localization of manifest accessory pathways in both children and adults: SMART-WPW. Heart Rhythm. Published 3 May 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →