Arrhythmias & electrophysiology
A novel endocardial activation–derived predictor for focal paraseptal atrial tachycardias: Evidence from a multicenter cohort study
Authors' conclusion
ΔRA-LA is a useful endocardial activation-derived parameter for predicting the successful ablation site of PSAT.
Study context
- Population
- Patients with paraseptal atrial tachycardia (PSAT) ablation; 11 men (25%), mean age 62.6 ± 14.7 years
- Participants
- 44 patients
- Exposure
- Ablation-site groups compared by ΔRA-LA, ΔRA-NCC and ΔLA-NCC
- Group 1n = 10
- Group 2n = 13
- Group 3n = 21
- Outcome
- Endocardial activation-derived predictor of the PSAT ablation site
Methodological details4 tertiary medical centres
- 4 tertiary medical centres
Main finding
As reported in the abstract
ΔRA-LA for predicting PSAT ablation site
- ΔRA-LA, right para-Hisian vs noncoronary cusp (NCC) ablation: AUC
- 1.000
- ΔRA-LA, right para-Hisian vs NCC ablation: sensitivity
- 100%
- ΔRA-LA, right para-Hisian vs NCC ablation: specificity
- 100%
- ΔRA-LA, right para-Hisian vs NCC ablation: cutoff
- 7 ms
- ΔRA-LA, NCC vs left paraseptal ablation: AUC
- 0.974
- ΔRA-LA, NCC vs left paraseptal ablation: sensitivity
- 92.3%
- ΔRA-LA, NCC vs left paraseptal ablation: specificity
- 95.2%
- ΔRA-LA, NCC vs left paraseptal ablation: cutoff
- −4 ms
- 2-step algorithm: PPV
- 95.4%
- 2-step algorithm: NPV
- 97.0%
Observational data: associations, not effects.
Original publication
A novel endocardial activation–derived predictor for focal paraseptal atrial tachycardias: Evidence from a multicenter cohort study. Heart Rhythm. Published 15 June 2024. doi:10.
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