Valvular & structural heart disease
A propensity-matched comparison of plug- versus suture-based vascular closure after transcatheter aortic valve implantation (TAVI)
Authors' conclusion
P-VCD were associated with higher rates of primary access-related vascular complications, driven by minor complications, compared to S-VCD. Endovascular treatment was more common after P-VCD failure.
Study context
- Population
- Consecutive patients who had undergone transfemoral TAVI, 2016 to 2021consecutive patients evaluated, matched 900 P-VCD and 1,800 S-VCD
- Participants
- 10,120 patients
- Exposure
- P-VCD vs S-VCD strategies after transfemoral TAVI
- P-VCDn = 900
- S-VCDn = 1,800
- Outcome
- Major and minor access-related vascular complications at the primary access site (VARC-3)
Methodological detailsretrospective, propensity score matched 1:2, 10 centres
- Retrospective
- Propensity score matched 1:2
- 10 centres
Main finding
As reported in the abstract
Major and minor access-related vascular complications at the primary access site (VARC-3)
Major
Minor
Observational data: associations, not effects.
Further findings
Bleeding
Treatment of bleeding
Endovascular balloon inflation
Stent implantation
Surgical repair
- Bleeding: p=0.028
- Treatment of bleeding: balloon inflation p<0.001
- Treatment of bleeding: stent implantation p<0.001
- Treatment of bleeding: surgical repair p=0.03
Baseline characteristics
- Median age
- 81.8 years
- Female
- 46.4%
- Median European System for Cardiac Operative Risk Evaluation II
- 3.50%
Original publication
A propensity-matched comparison of plug- versus suture-based vascular closure after TAVI. EuroIntervention. Published 3 March 2025. doi:10. 4244/ eij-d-24-00120
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