Valvular & structural heart disease

A propensity-matched comparison of plug- versus suture-based vascular closure after transcatheter aortic valve implantation (TAVI)

EuroInterventionPublished registry

Authors' conclusion

P-VCD were associated with higher rates of primary access-related vascular complications, driven by minor complications, compared to S-VCD. Endovascular treatment was more common after P-VCD failure.

Study context

Population
Consecutive patients who had undergone transfemoral TAVI, 2016 to 2021consecutive patients evaluated, matched 900 P-VCD and 1,800 S-VCD
Participants
10,120 patients
Exposure
P-VCD vs S-VCD strategies after transfemoral TAVI
  • P-VCDn = 900
  • S-VCDn = 1,800
Outcome
Major and minor access-related vascular complications at the primary access site (VARC-3)
Methodological detailsretrospective, propensity score matched 1:2, 10 centres
  • Retrospective
  • Propensity score matched 1:2
  • 10 centres

Main finding

As reported in the abstract

Major and minor access-related vascular complications at the primary access site (VARC-3)

Major

Minor

Observational data: associations, not effects.

Further findings

Bleeding

Treatment of bleeding

Endovascular balloon inflation

Stent implantation

Surgical repair

  • Bleeding: p=0.028
  • Treatment of bleeding: balloon inflation p<0.001
  • Treatment of bleeding: stent implantation p<0.001
  • Treatment of bleeding: surgical repair p=0.03

Baseline characteristics

Median age
81.8 years
Female
46.4%
Median European System for Cardiac Operative Risk Evaluation II
3.50%

Original publication

A propensity-matched comparison of plug- versus suture-based vascular closure after TAVI. EuroIntervention. Published 3 March 2025. doi:10.4244/eij-d-24-00120

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