Accelerometer-based sedentary time and physical activity from childhood through young adulthood with progressive cardiac changes: a 13-year longitudinal study
Authors' conclusion
ST contributed +40% to the 7-year increase in cardiac mass, MVPA increased cardiac mass by +5%, but LPA reduced cardiac mass by -49%.
Study context
- Population
- UK birth cohort children aged 11 years followed to young adulthood, with repeated echocardiography at ages 17 and 24 years1,054 [62.7%] females
- Participants
- 1,682 children
- Comparison
- Cumulative accelerometer-measured sedentary time (ST), LPA and MVPA from age 11 to 24 years
- Primary endpoint
- Longitudinal changes in cardiac structure and function: Left ventricular (LV) mass indexed for height2.7 (LVMI2.7) and LV diastolic function (mitral E/A ratio, LVDF)
- Follow-up
- Ages 17 and 24 years
Methodological detailsprospective observational, 13-year longitudinal
- Prospective observational
- 13-year longitudinal
Primary result
As reported in the abstract
LVMI2.7 change from ages 11 to 24 years
Effect estimate
0.002 g/m2.7
CI 0.001–0.003P < 0.001
Cumulative one-min/day increase in ST · irrespective of sex, obesity and hypertensive status
Effect estimate
−0.005 g/m2.7
CI −0.006 to −0.003P < 0.0001
Cumulative one-min/day increase in LPA
Effect estimate
0.003 g/m2.7
CI 0.001–0.006P = 0.015
Cumulative one-minute/day increase in MVPA
Further findings
Contribution to 7-year increase in cardiac mass
- ST
- +40%
- MVPA
- +5%
- LPA
- −49%
Original publication
Accelerometer-based sedentary time and physical activity from childhood through young adulthood with progressive cardiac changes: a 13-year longitudinal study. Eur J Prev Cardiol. Published 7 May 2024. doi:10.
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