Prevention & lipids

Accelerometer-Derived “Weekend Warrior” Physical Activity and Incident Cardiovascular Disease

JAMAPublished Retrospective cohort study

Authors' conclusion

Physical activity concentrated within 1 to 2 days was associated with similarly lower risk of cardiovascular outcomes to more evenly distributed activity.

Study context

Population
UK Biobank participants with a full week of accelerometer data, 2013–2015
Participants
89,573 participants
Exposure
Active weekend warrior vs active regular vs inactive MVPA patterns
  • Active WWn = 37,872
  • Active regularn = 21,473
  • Inactiven = 30,228reference
Outcome
Incident AF, MI, HF, stroke (threshold ≥150 min/wk)
Methodological detailsUK Biobank
  • UK Biobank

Main finding

As reported in the abstract

GroupAF HRMI HRHF HRStroke HR
Active WW0.78 (95% CI 0.74-0.83)0.73 (95% CI 0.67-0.80)0.62 (95% CI 0.56-0.68)0.79 (95% CI 0.71-0.88)
Active regular0.81 (95% CI 0.74-0.88)0.65 (95% CI 0.57-0.74)0.64 (95% CI 0.56-0.73)0.83 (95% CI 0.72-0.97)
Inactive1.00 (95% CI 0.94-1.07)1.00 (95% CI 0.91-1.10)1.00 (95% CI 0.92-1.09)1.00 (95% CI 0.90-1.11)

AF HR

Active WW0.78 (95% CI 0.74-0.83)
Active regular0.81 (95% CI 0.74-0.88)
Inactive1.00 (95% CI 0.94-1.07)

MI HR

Active WW0.73 (95% CI 0.67-0.80)
Active regular0.65 (95% CI 0.57-0.74)
Inactive1.00 (95% CI 0.91-1.10)

HF HR

Active WW0.62 (95% CI 0.56-0.68)
Active regular0.64 (95% CI 0.56-0.73)
Inactive1.00 (95% CI 0.92-1.09)

Stroke HR

Active WW0.79 (95% CI 0.71-0.88)
Active regular0.83 (95% CI 0.72-0.97)
Inactive1.00 (95% CI 0.90-1.11)

Observational data: associations, not effects.

Further findings

OutcomeActive WWActive regularInactive
Stroke at median threshold (≥230.4 min/wk MVPA)
Stroke HR0.89 (95% CI 0.79-1.02)0.87 (95% CI 0.74-1.02)1.00 (95% CI 0.90-1.11)

Stroke at median threshold (≥230.4 min/wk MVPA)

Findings consistent at median threshold; stroke associations no longer significant

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Accelerometer-Derived “Weekend Warrior” Physical Activity and Incident Cardiovascular Disease. JAMA. Published 18 July 2023. doi:10.1001/jama.2023.10875

Composed by AI from the published abstract and checked against it. How Briefs are made →

Get them every week

New studies on this topic in My Week and in your Monday e-mail.

We e-mail you a sign-in link and a code. No password, no spam.