Valvular & structural heart disease
Accelerometer-Measured Physical Activity After Mitral Valve Surgery: An Analysis of the UK Mini Mitral Randomized Controlled Trial
Authors' conclusion
The data support an overall decline from baseline activity to 52 weeks in patients undergoing a sternotomy and an earlier recovery of physical activity after a minimally invasive thoracoscopically guided right minithoracotomy approach.
Study context
- Population
- Patients undergoing mitral valve repair in the UK Mini Mitral trial, with valid wrist-worn accelerometry datavalid accelerometry data
- Participants
- 230 patients
- Comparison
- Mini vs Sternotomy
- Minin = 115
- Sternotomyn = 115reference
Methodological detailsblinded outcome analysis, Secondary analysis using a different primary end point, Wrist-worn triaxial accelerometer for 24 h over 7 days before surgery and at 6, 12, 18, 24, 38 and 52 weeks after surgery
- Blinded outcome analysis
- Secondary analysis using a different primary end point
- Wrist-worn triaxial accelerometer for 24 h over 7 days before surgery and at 6, 12, 18, 24, 38 and 52 weeks after surgery
Primary result
As reported in the abstract
Total activity counts
- 6 weeks
- mean difference 26 744 (95% CI 9085-44 403); P = 0.003
- 18 weeks
- mean difference 26 060 (95% CI 6971-45 149); P = 0.008
Further findings
| Outcome | Mean difference (minutes per day) (95% CI) | P value | |
|---|---|---|---|
| Time in moderate-to-vigorous physical activity — Mini vs Sternotomy · 6 weeks | 15 (5.7–24) | P = 0.001 | |
| Time in moderate-to-vigorous physical activity — Mini vs Sternotomy · 18 weeks | 9.9 (0.31–20) | P = 0.043 | |
| −100102030Difference, minutes per day (linear scale) |
Sedentary time and light physical activity
- Significantly lower sedentary time with Mini (at 12, 18 and 24 weeks)
- More time in light physical activity with Mini (at 18 weeks)
Sleep duration and sleep efficiency
- No differences in sleep duration between arms at any time point
- Higher sleep efficiency with Mini at 12 weeks
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Accelerometer-Measured Physical Activity After Mitral Valve Surgery: An Analysis of the UK Mini Mitral Randomized Controlled Trial. Circulation. Published 5 September 2025. doi:10.
Summarised from the published abstract; every number is checked against it