Coronary disease & ACSCohort study
Acute Response of the Noninfarcted Myocardium and Surrounding Tissue Assessed by T2 Mapping After STEMI
- Prospective cohort study
- consecutive patients
- Median time from primary PCI to CMR 3 days (IQR: 2-5 days)
Authors' conclusion
Higher NIM T2 values after STEMI are independently associated with worse cardiovascular outcomes, mainly because of higher risk of myocardial infarction.
Study context
- Population
- Patients with STEMI without prior CV events undergoing CMR after primary PCIfollow-up available for 130
- Participants
- 171 patients
- Exposure
- Higher vs ≤45 ms noninfarcted myocardium (NIM) T2 values
- Outcome
- Major adverse cardiac events (MACE):
- CV death
- MI
- Unplanned coronary revascularization
- Rehospitalization for HF
- Follow-up
- Median 17 months
Main finding
MACE
Hazard ratio
2.824
95% CI 1.254–6.361
P = 0.012
higher NIM T2 values vs NIM T2 ≤45 ms
HR 2.824 (95% CI 1.254–6.361); P = 0.012
As reported in the abstract
Observational data: associations, not effects.
Further findings
Myocardial reinfarction · median follow-up 17 months
P < 0.001
Correlates of higher NIM T2 values
- Associated with larger infarct size, microvascular obstruction and LV dysfunction
- No correlation with C-reactive protein, white blood cells, or T2 values of pectoralis muscle, liver and spleen
Original publication
Acute Response of the Noninfarcted Myocardium and Surrounding Tissue Assessed by T2 Mapping After STEMI. JACC Cardiovasc Imaging. Published 24 January 2024. doi:10.1016/j.jcmg.2023.11.014
Summarised from the published abstract; every number is checked against it