Prevention & lipidsCohort study
Added predictive value of childhood physical fitness to traditional risk factors for adult cardiovascular disease
- Prospective cohort study
- longitudinal
Authors' conclusion
Cardiorespiratory fitness and muscular fitness are independent health indicators that could complement other risk factors in childhood to identify individuals at increased long-term CV risk.
Study context
- Population
- Childhood Determinants of Adult Health Study participants assessed as children in 1985 and as adultsn range 578–5049
- Exposure
- Traditional childhood risk factors with vs without childhood cardiorespiratory fitness (CRF) or muscular fitness
- Outcome
- Adult obesity, hypertension, dyslipidaemia and metabolic syndrome (MetS) predicted by childhood fitness over traditional childhood CV risk factors
- Follow-up
- Mean 27 years
Main finding
As reported in the abstract
Adult obesity, low HDL-C and MetS: added predictive value of childhood CRF or muscular fitness
Increment in AUC (Δrange)
0.003-0.022
Net reclassification index (range)
0.026-0.149
Integrated discrimination index (range)
0.003-0.027
Observational data: associations, not effects.
Original publication
Added predictive value of childhood physical fitness to traditional risk factors for adult cardiovascular disease. Eur J Prev Cardiol. Published 24 February 2025. doi:10.1093/eurjpc/zwaf102
Summarised from the published abstract; every number is checked against it