Additional value of cardiac magnetic resonance parametric mapping in tissue characterization of common benign paediatric cardiac tumours
Authors' conclusion
Mass mapping analysis is feasible and reproducible in children. ECV values provide the most accurate differentiation. Mass ECV consistently resembles normal myocardium in rhabdomyoma, is extremely high (approaching 100%) in fibroma, equals to zero in lipoma, and matches blood pool ECV (1-Hct) in haemangioma.
Study context
- Population
- Paediatric patients referred for cardiac tumours who underwent cardiac magnetic resonance (CMR) with mapping sequences, Bambino Gesù Children's Hospital, June 2017–November 2023mean age 7 ± 5 years
- Participants
- 16 patients
- Exposure
- CMR native T1 and extracellular volume (ECV) mapping across benign paediatric cardiac tumour types
- Group An = 3
- Group Bn = 4
- Group Cn = 6
- Group Dn = 3
- Outcome
- Mass native T1 and ECV by tumour type
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
| Group | Native T1 | ECV |
|---|---|---|
| Group A | 1465 ± 158 ms | 54 ± 4% |
| Group B | 860 ± 118 ms | 93 ± 4% |
| Group C | 1007 ± 57 ms | 23 ± 5% |
| Group D | 215 ± 13 ms | 0 ± 0% |
Native T1
Group A1465 ± 158 ms
Group B860 ± 118 ms
Group C1007 ± 57 ms
Group D215 ± 13 ms
ECV
Group A54 ± 4%
Group B93 ± 4%
Group C23 ± 5%
Group D0 ± 0%
- Significant differences in mass native T1 and ECV among the four subgroups (ANOVA)
- P < 0.001
Observational data: associations, not effects.
Original publication
Additional value of cardiac magnetic resonance parametric mapping in tissue characterization of common benign paediatric cardiac tumours. Eur Heart J Cardiovasc Imaging. Published 25 July 2024. doi:10.
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