Arrhythmias & electrophysiology
Electrophysiological and Histopathological Characteristics of Ventricular Tachycardia Associated With Primary Cardiac Tumors
Authors' conclusion
The mechanism underlying PCT-VT involves re-entry localized at the tumor edges. Myocardial disarray associated with tumor infiltration is a substrate for this form of VT. Cryoablation along the border between the tumor and myocardium is a promising therapeutic option for unresectable PCT-VT.
Study context
- Population
- Patients aged 1 to 34 years with ventricular tachycardia (VT) associated with primary cardiac tumors (fibroma, lipoma, hamartoma) undergoing surgery for VT, 1981–2020of 67 operated for VT
- Participants
- 4 patients
- Outcome
- Mechanism and substrate of PCT-VT
Methodological detailssingle-centre, intraoperative electroanatomical mapping, histopathological study
- Single-centre
- Intraoperative electroanatomical mapping
- Histopathological study
Main finding
As reported in the abstract
Electrical storms of sustained VTs refractory to multiple drugs and repetitive endocardial ablations
All 4 patients
Observational data: associations, not effects.
Further findings
Encircling cryoablation isolating unresectable tumor
- Effective in suppressing VT in patients in whom complete resection was unfeasible
- 2
Original publication
Electrophysiological and Histopathological Characteristics of Ventricular Tachycardia Associated With Primary Cardiac Tumors. JACC Clin Electrophysiol. Published 18 October 2023. doi:10.
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