Heart failure & cardiomyopathies

Advanced prediction of heart failure risk in elderly diabetic and hypertensive patients using nine machine learning models and novel composite indices: insights from NHANES 2003–2016

Eur J Prev CardiolPublished Cross-sectional study

Authors' conclusion

The study demonstrates that novel composite indices like ABSI, AIP, BARD score, BFP, BRI, FLI, and PNI have significant potential in predicting HF risk among elderly diabetic and hypertensive patients.

Study context

Population
Elderly patients (aged 65 and above) with both diabetes and hypertension, NHANES 2003–2016of 71,058 NHANES subjects
Participants
1,445 patients
Outcome
HF status
Methodological detailsmachine learning prediction models, NHANES 2003–2016, Missing values imputed using random forest algorithms, Feature importance by SHAP values
  • Machine learning prediction models
  • NHANES 2003–2016
  • Missing values imputed using random forest algorithms
  • Feature importance by SHAP values

Main finding

As reported in the abstract

HF prediction
GroupAUC
XGBoost0.96

XGBoost

AUC0.96

Observational data: associations, not effects.

Original publication

Advanced prediction of heart failure risk in elderly diabetic and hypertensive patients using nine machine learning models and novel composite indices: insights from NHANES 2003–2016. Eur J Prev Cardiol. Published 27 February 2025. doi:10.1093/eurjpc/zwaf081

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