Heart failure & cardiomyopathies
A body shape index for visceral fat and its changes predict cardiovascular outcomes of heart failure with preserved ejection fraction
Authors' conclusion
ABSI was independently associated with long-term prognosis in patients with HFpEF, and a history of high ABSI was associated with a poorer prognosis later in life
Study context
- Population
- Patients with Heart Failure with Preserved Ejection Fraction (HFpEF) in the Treatment of Preserved Cardiac Function Heart Failure with an Aldosterone Antagonist trialmean follow-up 3.9 years
- Participants
- 3,319 patients
- Comparison
- A body shape index (ABSI) tertiles
Primary result
As reported in the abstract
CV outcomes by ABSI tertile (multivariate-adjusted) · mean follow-up 3.9 years
ABSI >0.084 vs ABSI ≤0.078Hazard ratio (95% CI)
All-cause mortality
1.464(1.150–1.864)
CV death
1.685(1.241–2.289)
MI
1.778(1.088–2.904)
MACE
1.430(1.123–1.822)
Further findings
Previous or current high ABSI
| HR (95% CI) | ||
|---|---|---|
| Previous or current high ABSIAll-cause mortality | 1.635 (1.116–2.396) | |
| Previous or current high ABSICV death | 1.724 (1.071–2.775) | |
| Previous or current high ABSIMI | 2.021 (0.878–4.653) | |
| Previous or current high ABSIMACE | 1.653 (1.117–2.447) | |
| 0.20.5125Hazard ratio (log scale) |
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
A body shape index for visceral fat and its changes predict cardiovascular outcomes of heart failure with preserved ejection fraction. Eur Heart J Qual Care Clin Outcomes. Published 28 February 2025. doi:10. 1093/ ehjqcco/ qcaf005
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