Prevention & lipids

Age- and Sex-Specific Nomographic CT Quantitative Plaque Data From a Large International Cohort

JACC Cardiovasc ImagingPublished Cross-sectional study

Authors' conclusion

The authors developed pragmatic age- and sex-stratified percentile nomograms for atherosclerotic plaque measures using findings from coronary CTA.

Study context

Population
Patients undergoing clinically indicated coronary computed tomographic angiography (CTA), large international multicentre cohortmean age 62.7 ± 12.2 years
Participants
11,808 patients
Exposure
Male vs female participants
  • Femalen = 5,423reference
Outcome
Total atherosclerotic plaque and plaque subtype volumes (age- and sex-specific nomograms)
Methodological detailsmulticentre, consecutive cohort, AI-enabled quantitative plaque analysis
  • Multicentre
  • Consecutive cohort
  • AI-enabled quantitative plaque analysis

Main finding

As reported in the abstract

Total plaque volume

P < 0.0001

Observational data: associations, not effects.

Original publication

Age- and Sex-Specific Nomographic CT Quantitative Plaque Data From a Large International Cohort. JACC Cardiovasc Imaging. Published 5 July 2023. doi:10.1016/j.jcmg.2023.05.011

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