Prevention & lipidsCross-sectional study
Age and Sex-Specific Percentiles of 30-Year Cardiovascular Disease Risk Based on the PREVENT Equations
- Cross-sectional study
- nationally representative sample
Online tool developed to present risk percentiles alongside absolute 30-year risk
Authors' conclusion
Population-based age- and sex-specific percentiles for 30-year CVD risk with PREVENT may offer a complementary tool for clinicians and patients in addition to communicating absolute CVD risk estimates.
Study context
- Population
- US adults aged 30–59 years without prevalent cardiovascular disease (CVD), National Health and Nutrition Examination Survey (NHANES) 2011 to March 2020≈91 million US adults represented
- Participants
- 8,686 participants
- Exposure
- Women vs Men
- Outcome
- Age- and sex-specific percentiles of 30-year CVD, ASCVD and HF risk estimated with PREVENT
Main finding
As reported in the abstract
30-year CVD risk (PREVENT)
50th percentile at age 45
75th percentile at age 45
- Median 30-year CVD risk, overall sample
- 13.1%
Observational data: associations, not effects.
Further findings
30-year atherosclerotic cardiovascular disease (ASCVD) and heart failure (HF) risk
- Similar patterns, with higher 30-year absolute risk in men than women
Original publication
Age and Sex-Specific Percentiles of 30-Year Cardiovascular Disease Risk Based on the PREVENT Equations. J Am Coll Cardiol. Published 25 November 2025. doi:10.1016/j.jacc.2025.09.1509
Summarised from the published abstract; every number is checked against it