Coronary disease & ACS

Comprehensive diagnosis in chronic coronary syndromes combining angiography and intracoronary testing: the AID-ANGIO study

EuroInterventionPublished all-comers, prospective, multicentre study

Authors' conclusion

In assessing ischaemia-generating coronary abnormalities, prespecified use of the AID strategy was associated with a 2.6-fold increase in diagnostic yield compared with ICA (84.2% vs 32.2%, respectively), largely due to the identification of INOCA. Modification of the therapeutic plan with the AID strategy occurred in 59.9% of cases. (ClinicalTrials.gov: NCT05635994).

Study context

Population
Chronic coronary syndromes (CCS) patients referred for invasive coronary angiography (ICA)44.2% female
Participants
317 patients
Exposure
Advanced invasive diagnosis (AID) strategy compared with ICA
Outcome
Proportion of patients with a cause of ischaemia identified by the AID strategy

Main finding

As reported in the abstract

Proportion of patients with a cause of ischaemia identified by the AID strategy

Obstructive CAD

INOCA AID strategy 45.1%

  • AID strategy vs ICA: P < 0.001

Observational data: associations, not effects.

Further findings

No abnormalities

Patients without any abnormalities
15.8%

Modification of the original treatment plan with the AID strategy

Treatment plan modified
59.9%

Original publication

Comprehensive diagnosis in chronic coronary syndromes combining angiography and intracoronary testing: the AID-ANGIO study. EuroIntervention. Published 6 January 2025. doi:10.4244/eij-d-24-00499

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