Prevention & lipidsCohort study

Alcohol Consumption and Incident Heart Failure in Men and Women

Eur J Heart FailPublished

  • Prospective cohort study
  • UK Biobank
  • competing-risk model
  • cubic spline regression

Authors' conclusion

Alcohol consumption was higher among men compared with women. Although low to moderate total alcohol consumption appears to be associated with a reduced risk of developed HF, beer drinkers, particularly women, were at higher risk of developed HF.

Study context

Population
UK Biobank participants without a history of heart failure (HF) at baseline who completed alcohol questionnaires (52% women, age 56 years)
Participants
407,014 participants
Exposure
Levels of alcohol consumption and incident HF, by sex
Outcome
Incident HF
Follow-up
Median 12 years

Main finding

As reported in the abstract

Incident HF by total alcohol consumption

Incident HF cases (34% women)

11 735

Observational data: associations, not effects.

Further findings

Total alcohol consumption, men vs women

P < 0.001

Wine consumption and incident HF

Similar trends to total alcohol consumption

Beer consumption and incident HF

7-14 units/week of beer in women: increased risk of incident HF
29%
HF risk increases with beer consumption, particularly in women
  • p for sex interaction = 0.002

Original publication

Alcohol Consumption and Incident Heart Failure in Men and Women. Eur J Heart Fail. Published 20 January 2025. doi:10.1002/ejhf.3587

Summarised from the published abstract; every number is checked against it