Arrhythmias & electrophysiology
Alcohol is neither a risk factor nor a protective factor for sudden cardiac death and/or fatal ventricular arrhythmia: A population-based study with genetic traits and alcohol consumption in the UK Biobank
Authors' conclusion
Alcohol consumption was neither a protective factor nor a risk factor for sudden cardiac death or fatal ventricular arrhythmia. Genetic traits of alcohol metabolism were not associated with the clinical prognosis.
Study context
- Population
- Individuals enrolled 2006–2010 in the UK Biobank, followed until 20213,543 cases (0.89%)
- Participants
- 397,164 individuals
- Exposure
- Alcohol consumption categories and genetic traits for alcohol metabolism
- Outcome
- Composite of:
- SCD
- Fatal ventricular arrhythmia
- Follow-up
- Median 12.5 years
Methodological detailspopulation-based, UK Biobank
- Population-based
- UK Biobank
Main finding
As reported in the abstract
SCD and/or fatal ventricular arrhythmia
Hazard ratio (95% CI)
Ex-drinkersvs Current nondrinkersadjusted for covariates; increased risk in univariate analysis attenuated
1.19(0.94–1.50)
Alcohol consumption (continuous)
1.01(0.99–1.02)
Observational data: associations, not effects.
Original publication
Alcohol is neither a risk factor nor a protective factor for sudden cardiac death and/or fatal ventricular arrhythmia: A population-based study with genetic traits and alcohol consumption in the UK Biobank. Heart Rhythm. Published 1 May 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →